The center of athletics at Mercersburg is Nolde Gymnasium, which houses a nine-lane swimming pool, three basketball courts, the new Davenport Squash Center and other facilities.

Additional athletic facilities include 14 tennis courts at the Smoyer Tennis Center, a 400-meter all-weather track, jumping pits, 10 playing fields, and an outdoor sand volleyball court.  The skiing and golf teams utilize the nearby Whitetail Golf course and Whitetail Mountain ski slopes. Facilities for Mercersburg Outdoor Education (MOE) program are centered in a renovated red barn outfitted with an indoor climbing wall.